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Lida Zoetekouw Selected Research

Dihydropyrimidinase Deficiency

12/2017Dihydropyrimidinase deficiency in four East Asian patients due to novel and rare DPYS mutations affecting protein structural integrity and catalytic activity.
10/2003Dihydropyrimidinase deficiency and severe 5-fluorouracil toxicity.

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Lida Zoetekouw Research Topics

Disease

8Dihydropyrimidine Dehydrogenase Deficiency
01/2018 - 09/2002
3Neoplasms (Cancer)
01/2016 - 09/2002
3Neutropenia
06/2008 - 09/2002
2Dihydropyrimidinase Deficiency
12/2017 - 10/2003
1Psychotic Disorders (Schizoaffective Disorder)
01/2019
1Infantile Spasms (West Syndrome)
12/2017
1Atrophy
12/2017
1Neurodevelopmental Disorders
01/2015
1Purine Nucleoside Phosphorylase Deficiency
01/2015
1Ataxia (Dyssynergia)
01/2015
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/2015
1Lysosomal Storage Diseases (Lysosomal Storage Disease)
07/2013
1Mucopolysaccharidosis I (Hurler Syndrome)
07/2013
1Intellectual Disability (Idiocy)
07/2012
1Microcephaly
07/2012
1Seizures (Absence Seizure)
07/2012
1Pancytopenia
06/2008
1Infections
06/2008
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2008
1Pneumonia (Pneumonitis)
06/2008
1Beta-Ureidopropionase Deficiency
11/2004

Drug/Important Bio-Agent (IBA)

5Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
01/2018 - 10/2002
5Fluorouracil (Carac)FDA LinkGeneric
06/2009 - 09/2002
3pyrimidineIBA
06/2009 - 11/2004
2Capecitabine (Xeloda)FDA Link
01/2018 - 06/2008
2EnzymesIBA
07/2013 - 10/2002
1Biomarkers (Surrogate Marker)IBA
01/2019
1Antipsychotic Agents (Antipsychotics)IBA
01/2019
1Dopa DecarboxylaseIBA
01/2019
1Proteins (Proteins, Gene)FDA Link
12/2017
15,6-dihydrothymineIBA
12/2017
1Nonsense Codon (Nonsense Mutation)IBA
01/2016
1UracilIBA
01/2016
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2015
1Iduronidase (alpha-L-Iduronidase)IBA
07/2013
1AcidsIBA
07/2012
1Alanine (L-Alanine)FDA Link
07/2012
1Antineoplastic Agents (Antineoplastics)IBA
06/2009
1Azathioprine (Imuran)FDA LinkGeneric
06/2008
1thiopurine methyltransferase (thiopurine S-methyltransferase)IBA
06/2008
1phytobacteriomycin (PBM)IBA
01/2007
13-aminoisobutyric acidIBA
11/2004
1beta-AlanineIBA
11/2004

Therapy/Procedure

2Therapeutics
01/2015 - 06/2008
1Drug Tapering
01/2018
1Hematopoietic Stem Cell Transplantation
01/2015